"Product Information. Pantoprazole is used to treat certain stomach and esophagus problems (such as acid reflux). Cerner Multum, Inc. "UK Summary of Product Characteristics." Info aboutPantoprazole. Like all medicines, pantoprazole can cause side effects, although not everyone gets them. Pantoprazole is available OTC and in generic form. Side Effects for PANTOPRAZOLE (tablet, delayed release) are also known as adverse reactions. The latter also applies to most of the other specific side effects of pantoprazole. These factors may affect how you should use this medication. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. However, it can cause other side effects. At www.pantoprazolesideeffects.com we are providing tips and valuable information for our visitors looking to get more information about Pantoprazole Side Effects.This website is for is only for informational purposes. Side effects. [Ref], Uncommon (0.1% to 1%): Fracture of the hip/wrist/spine, Very rare (less than 0.01%): Skeletal pain, Frequency not reported: Bone fracture, elevated creatine phosphokinase (CPK)/elevated creatine kinase (CK), muscle spasm, systemic lupus erythematosus, Postmarketing reports: Rhabdomyolysis[Ref], Rare (0.01% to 0.1%): Hyperlipidemia, increased cholesterol, increased triglycerides, lipid increases, weight changes, Frequency not reported: Cyanocobalamin (vitamin B12) deficiency), electrolyte disturbances, hypocalcemia, hypokalemia, hypomagnesemia, hyponatremia, potential for exacerbation of zinc deficiency[Ref]. Below is a summary of known side effects for Pantoprazole. Pantoprazole reduces the amount of acid produced in your stomach. Call your doctor at once if you have: severe stomach pain, diarrhea that is watery or bloody; sudden pain or trouble moving your hip, wrist, or back; Pantoprazole side effects. You may report them to the FDA. These side effects may go away during treatment as your body adjusts to the medicine. Any use of this site constitutes your agreement to the Terms and Conditions and Privacy Policy linked below. Pantoprazole may increase your risk of having fractures of the hip, wrist, and spine. Before you begin using a medication, be sure to inform your doctor of any medical conditions or allergies you may have, any medications you are taking, whether you are pregnant or breast-feeding, and any other significant facts about your health. Check with your doctor immediately if any of the following side effects occur while taking pantoprazole: Some side effects of pantoprazole may occur that usually do not need medical attention. "Product Information. The following information comes from DailyMed, an FDA label information provider. We look at pantoprazole’s uses, dosage, and side effects, and what to know before taking it. 18 December, 2018 . omeprazole, amoxicillin, famotidine, pantoprazole, metronidazole, Nexium, ranitidine, Protonix, Pepcid, Prilosec. Call your doctor if you have any unusual problems while taking this medication. This is more likely if you take several doses per day or use it for one year or more. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them: Applies to pantoprazole: intravenous powder for injection, oral delayed release tablet, oral granule enteric coated, The most commonly reported side effects were headache, diarrhea, and injection site thrombophlebitis (in IV formulations). According to studies, they affect 5 percent of patients. Adverse Reactions. Rebound acid secretion. [Ref], Common (1% to 10%): Injection site thrombophlebitis, Frequency not reported: Injection site reactions[Ref], Common (1% to 10%): Influenza-like symptoms, moniliasis, Rare (0.01% to 0.1%): Anaphylactic reactions, anaphylactic shock, angioedema/Quincke's edema, hypersensitivity, hypersensitivity reactions, Frequency not reported: Allergic reactions, Rare (0.01% to 0.1%): Agranulocytosis, anemia, Very rare (less than 0.01%): Increased coagulation time, leukopenia, pancytopenia, thrombocytopenia[Ref], Uncommon (0.1% to 1%): Blurred vision, visual disturbances, Very rare (less than 0.01%): Conjunctivitis[Ref], Very rare (less than 0.01%): Interstitial nephritis (with possible progression to renal failure), Frequency not reported: Acute interstitial nephritis[Ref], 1. Pantoprazole(also known as Protonix, Protium or Pantoloc) is the drug used to treat acid reflux, Zollinger-Ellison syndrome and also ulcerations and erosion of esophagus in gastro-esophageal reflux disease (GERD). Medscape - Gastric ulcer, GERD, heartburn-specific dosing for Protonix (pantoprazole), frequency-based adverse effects, comprehensive interactions, contraindications, pregnancy & … The phase IV clinical study analyzes which people take Pantoprazole and have Chronic kidney disease. Some patients also report weight gain or the appearance of an irritable cough. Mayo Clinic does not endorse companies or products. Pantoprazole may increase your risk of having fractures of the hip, wrist, and spine. Diarrhea occurred most frequently in patients given quadruple therapy (pantoprazole, bismuth, metronidazole, tetracycline) for Helicobacter pylori infections, but was also very common in triple therapy (pantoprazole, amoxicillin, clarithromycin). Mayo Clinic facts about coronavirus disease 2019 (COVID-19), Our COVID-19 patient and visitor guidelines, plus trusted health information, Mayo Clinic Health System patient vaccination updates. [Ref], Nasopharyngitis and pharyngolaryngeal pain occurred in pediatric patients between the ages of 2 to 16 years. Stomach upset (such as feeling sick (nausea), stomach ache, or wind), tummy (abdominal) pain, being sick (vomiting) Stick to simple meals - avoid rich or spicy foods. Call your doctor right away if you have severe bone pain or are unable to walk or sit normally. Fecal and/or tongue discoloration occurred more commonly in patients given quadruple therapy versus patients given triple therapy. [Ref], Very common (10% or more): Headache (Up to 26.4%), taste pervasion (Up to 18.2%), Common (1% to 10%): Dizziness, metallic/bitter taste, somnolence, Very rare (less than 0.01%): Change to the sense of taste, reduced movement, speech disorder, Frequency not reported: Paresthesia, vertigo, Postmarketing reports: Ageusia, dysgeusia[Ref]. Side Effects What are the side effects of Pantoprazole (Protonix)?. If you experience side effects when taking Pantoprazole, be sure to tell your doctor. Pantoprazole sodium is a prescription medication indicated for the treatment of gastroesophageal reflux disease, severe inflammation of the esophagus and disorders in which excessive acid is secreted into the gastrointestinal tract. It works by decreasing the amount of acid your stomach makes. [Ref], Common (1% to 10%): Exanthema/exanthemata, rash, Uncommon (0.1% to 1%): Eruption, increased sweating, pruritus, Very rare (less than 0.01%): Erythema multiforme, flushing, Lyell syndrome, photosensitivity/photosensitivity reaction, severe skin reactions, Stevens-Johnson syndrome, toxic epidermal necrolysis (TEN), Frequency not reported: Cutaneous lupus erythematosus, facial edema, fatal skin reactions, fatal TEN, subacute cutaneous lupus erythematosus[Ref], Rare (0.01% to 0.1%): Hypertension, peripheral edema, thrombophlebitis, Very rare (less than 0.01%): Circulatory collapse, flushing, hot flushes, substernal chest pain, Frequency not reported: Generalized edema[Ref], Muscle spasm occurred as a consequence of electrolyte disturbances. The phase IV clinical study analyzes which people take Pantoprazole and have Withdrawal syndrome. In adults, headache occurred most frequently in patients given quadruple therapy (pantoprazole, bismuth, metronidazole, tetracycline) for H pylori infections, but was also very common in triple therapy (pantoprazole, amoxicillin, clarithromycin). [Ref], Common (1% to 10%): Depression (and all aggravations), Rare (0.01% to 0.1%): Confusion (and all aggravations), disorientation (and all aggravations), hallucination (and all aggravations), Common (1% to 10%): Increased liver enzymes (transaminases, GGT), Rare (0.01% to 0.1%): Increased bilirubin, Very rare (less than 0.01%): Cholestatic hepatitis, hepatitis, hepatocellular failure, jaundice, Frequency not reported: Hepatic effects, hepatocellular injury, liver function tests abnormal, Postmarketing reports: Hepatocellular damage[Ref], Severe hepatocellular damage leading to jaundice/hepatic failure is predicted to have a frequency of 1 in 1,000,000 patients. Caution with long-term use of pantoprazole. Some patients complain of dizziness, a sensation that the room is spinning, difficulty sleeping, unusual dreams, weakness, tense muscles, tingling hands or feet or ringing in the ears. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. pains in the stomach, side, or abdomen, possibly radiating to the back. Post a comment. Protonix (pantoprazole)" Wyeth-Ayerst Laboratories, Philadelphia, PA. blistering, peeling, or loosening of the skin, continuous ringing or buzzing or other unexplained noise in the ears, feeling of constant movement of self or surroundings, greatly decreased frequency of urination or amount of urine, large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or genitals, pains in the stomach, side, or abdomen, possibly radiating to the back, puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue, red skin lesions, often with a purple center, sores, ulcers, or white spots on the lips or in the mouth, excess air or gas in the stomach or bowels. All medicines can have side effects. How and when to take it. It works by decreasing the amount of acid your stomach makes. Some of the most commonly observed side effects of pantoprazole are nausea, headache, vomiting, and insomnia. Pantoprazole Side Effects. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. This site complies with the HONcode standard for trustworthy health information: verify here. In total, 108 (6.8%) patients experienced serious adverse events (EC definition), of which all but 6 were classified as being causally unrelated to pantoprazole (4 cases with 40 mg pantoprazole: colonic polyp; abdominal pain and rectal disorder; diarrhoea and abdominal pain, sepsis versus 2 cases with high dose pantoprazole: anaemia and hypertension (see Section 4.8 Adverse Effects (Undesirable Effects)). Pantoprazole is a proton pump inhibitor used in the treatment of stomach ulcers, gastroesophageal reflux disease (GERD) and other acidity-related disorders. All rights reserved. Pantoprazole side effects . Tell your doctor or pharmacist as soon as possible if you do not feel well while you are taking pantoprazole. [Ref], Very common (10% or more): Diarrhea (Up to 11.6%), Common (1% to 10%): Abdominal pain, benign fundic gland polyps/fundic gland polyps, buccal inflammation, constipation, dry mouth, dyspepsia, fecal discoloration, flatulence, heartburn, nausea, oral moniliasis, pruritus ani, tongue discoloration, tongue pain, upper abdominal pain, vomiting, Uncommon (0.1% to 1%): Abdominal discomfort/distention, bloating, loose stools, Rare (0.01% to 0.1%): Colon polyp, rectal disorder, Very rare (less than 0.01%): Increased saliva, Frequency not reported: Clostridium difficile-associated diarrhea, severe eructation[Ref], Uncommon (0.1% to 1%): Asthenia, fatigue, malaise, Rare (0.01% to 0.1%): Body temperature increased, fever, Very rare (less than 0.01%): Pain, tinnitus, Frequency not reported: Facial edema[Ref], Confusion, depression, hallucinations, and disorientation, especially in predisposed patients, occurred with use, and was aggravated in patients with preexisting conditions. ; Medically reviewed by Alexander Spillars Protonix, Pepcid, Prilosec once a day, first thing in stomach. 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